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HMGB1: The metabolic weapon in the arsenal of NK cells

Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein—a well-known proinflammatory cytokine—to specifically target glycolysis in cancer cells. This opens up new perspec...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Cerwenka, Adelheid, Kopitz, Jürgen, Schirmacher, Peter, Roth, Wilfried, Gdynia, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972106/
https://ncbi.nlm.nih.gov/pubmed/27652323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1175538
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