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HMGB1: The metabolic weapon in the arsenal of NK cells

Targeting tumor glycolysis would hit the main energy source of cancer. We show that natural killer (NK) cells pursue this strategy by employing high mobility group box 1 (HMGB1) protein—a well-known proinflammatory cytokine—to specifically target glycolysis in cancer cells. This opens up new perspec...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Oncol
Hoofdauteurs: Cerwenka, Adelheid, Kopitz, Jürgen, Schirmacher, Peter, Roth, Wilfried, Gdynia, Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972106/
https://ncbi.nlm.nih.gov/pubmed/27652323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1175538
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