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Iodide excess regulates its own efflux: a possible involvement of pendrin

Adequate iodide supply and metabolism are essential for thyroid hormones synthesis. In thyrocytes, iodide uptake is mediated by the sodium-iodide symporter, but several proteins appear to be involved in iodide efflux. Previous studies demonstrated that pendrin is able to mediate apical efflux of iod...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Calil-Silveira, Jamile, Serrano-Nascimento, Caroline, Kopp, Peter Andreas, Nunes, Maria Tereza
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971809/
https://ncbi.nlm.nih.gov/pubmed/26791486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00210.2015
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