Genetic and epigenetic regulation of intestinal fibrosis

Crohn’s disease affects those individuals with polygenic risk factors. The identified risk loci indicate that the genetic architecture of Crohn’s disease involves both innate and adaptive immunity and the response to the intestinal environment including the microbiome. Genetic risk alone, however, p...

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Bibliografiske detaljer
Udgivet i:United European Gastroenterol J
Main Authors: Li, Chao, Kuemmerle, John F
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2016
Fag:
Special section on Fibrosis in Crohn's disease and inflammatory bowel disorders
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971799/
https://ncbi.nlm.nih.gov/pubmed/27536359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2050640616659023
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