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Variant detection and runs of homozygosity in next generation sequencing data elucidate the genetic background of Lundehund syndrome

BACKGROUND: The Lundehund is a highly specialized breed characterized by a unique flexibility of the joints and polydactyly in all four limbs. The extremely small population size and high inbreeding has promoted a high frequency of diseased dogs affected by the Lundehund syndrome (LS), a severe gast...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Metzger, Julia, Pfahler, Sophia, Distl, Ottmar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971756/
https://ncbi.nlm.nih.gov/pubmed/27485430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2844-6
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