Selecting Cells for Bioartificial Liver Devices and the Importance of a 3D Culture Environment: A Functional Comparison between the HepaRG and C3A Cell Lines

Recently, the first clinical trials on Bioartificial Livers (BALs) loaded with a proliferative human hepatocyte cell source have started. There are two cell lines that are currently in an advanced state of BAL development; HepaRG and HepG2/C3A. In this study we aimed to compare both cell lines on ap...

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Bibliographic Details
Published in:Int J Biol Sci
Main Authors: van Wenum, Martien, Adam, Aziza A.A., Hakvoort, Theodorus B.M., Hendriks, Erik J., Shevchenko, Valery, van Gulik, Thomas M., Chamuleau, Robert A.F.M., Hoekstra, Ruurdtje
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971735/
https://ncbi.nlm.nih.gov/pubmed/27489500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.15165
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