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Epidermal growth factor receptor is expressed and active in a subset of acute myeloid leukemia

The epidermal growth factor receptor (EGFR) inhibitor erlotinib has been shown to induce complete remission of acute myeloid leukemia (AML) in two patients with concurrent lung cancer and raised attention for a role of EGFR in AML whereas a recent phase II clinical study with gefitinib in AML demons...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Mahmud, Hasan, Kornblau, Steven M., ter Elst, Arja, Scherpen, Frank J. G., Qiu, Yi Hua, Coombes, Kevin R., de Bont, Eveline S. J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971659/
https://ncbi.nlm.nih.gov/pubmed/27488458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0294-x
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