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Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli

The regulation of chromosomal replication is critical and the activation of DnaA by ATP binding is a key step in replication initiation. However, it remains unclear whether and how the process of ATP-binding to DnaA is regulated. Here, we show that DnaA can be acetylated, and its acetylation level v...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Qiufen, Zhou, Aiping, Li, Shuxian, Ni, Jinjing, Tao, Jing, Lu, Jie, Wan, Baoshan, Li, Shuai, Zhang, Jian, Zhao, Shimin, Zhao, Guo-Ping, Shao, Feng, Yao, Yu-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971506/
https://ncbi.nlm.nih.gov/pubmed/27484197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30837
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