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Evaluation of Giardia lamblia thioredoxin reductase as drug activating enzyme and as drug target
The antioxidative enzyme thioredoxin reductase (TrxR) has been suggested to be a drug target in several pathogens, including the protist parasite Giardia lamblia. TrxR is also believed to catalyse the reduction of nitro drugs, e.g. metronidazole and furazolidone, a reaction required to render these...
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| 出版年: | Int J Parasitol Drugs Drug Resist |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4971154/ https://ncbi.nlm.nih.gov/pubmed/27485086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2016.07.003 |
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