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Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains

Human aging is associated with cognitive decline and an increased risk of neurodegenerative disease. Our objective for this study was to evaluate potential relationships between age and variation in gene expression across different regions of the brain. We analyzed the Genotype-Tissue Expression (GT...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: Brinkmeyer-Langford, Candice L., Guan, Jinting, Ji, Guoli, Cai, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971101/
https://ncbi.nlm.nih.gov/pubmed/27536236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2016.00183
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