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Fluorescence-Based Strategies to Investigate the Structure and Dynamics of Aptamer-Ligand Complexes

In addition to the helical nature of double-stranded DNA and RNA, single-stranded oligonucleotides can arrange themselves into tridimensional structures containing loops, bulges, internal hairpins and many other motifs. This ability has been used for more than two decades to generate oligonucleotide...

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Détails bibliographiques
Publié dans:Front Chem
Auteurs principaux: Perez-Gonzalez, Cibran, Lafontaine, Daniel A., Penedo, J. Carlos
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971091/
https://ncbi.nlm.nih.gov/pubmed/27536656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2016.00033
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