Hydroxymethylation is uniquely distributed within term placenta, and is associated with gene expression

The conversion of cytosine to 5-methylcystosine (5mC) is an important regulator of gene expression. 5mC may be enzymatically converted to 5-hydroxymethylcytosine (5hmC), with a potentially distinct regulatory function. We sought to investigate these cytosine modifications and their effect on gene ex...

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Опубликовано в: :FASEB J
Главные авторы: Green, Benjamin B., Houseman, E. Andres, Johnson, Kevin C., Guerin, Dylan J., Armstrong, David A., Christensen, Brock C., Marsit, Carmen J.
Формат: Artigo
Язык:Inglês
Опубликовано: Federation of American Societies for Experimental Biology 2016
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Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970608/
https://ncbi.nlm.nih.gov/pubmed/27118675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600310R
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