TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway

We previously identified TDRG1 (testis developmental related gene 1), a novel gene with exclusive expression in testis, promoted the proliferation and progression of cultured human seminoma cells through PI3K/Akt/mTOR signaling. As increasing evidence reveal that aberrant activation of this signalin...

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Dettagli Bibliografici
Pubblicato in:Cancer Biol Ther
Autori principali: Gan, Yu, Wang, Yong, Tan, Zhengyu, Zhou, Jun, Kitazawa, Riko, Jiang, Xianzhen, Tang, Yuxin, Yang, Jianfu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970539/
https://ncbi.nlm.nih.gov/pubmed/27104982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1178425
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