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The potential of anti-malarial compounds derived from African medicinal plants, part III: an in silico evaluation of drug metabolism and pharmacokinetics profiling

BACKGROUND: Malaria is an endemic disease affecting many countries in Tropical regions. In the search for compound hits for the design and/or development of new drugs against the disease, many research teams have resorted to African medicinal plants in order to identify lead compounds. Three-dimensi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Org Med Chem Lett
Prif Awduron: Onguéné, Pascal Amoa, Ntie-Kang, Fidele, Mbah, James Ajeck, Lifongo, Lydia Likowo, Ndom, Jean Claude, Sippl, Wolfgang, Mbaze, Luc Meva′a
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Berlin Heidelberg 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4970435/
https://ncbi.nlm.nih.gov/pubmed/26548985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13588-014-0006-x
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