Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disorders

Early adversity increases risk for developing psychopathology. Epigenetic modification of stress reactivity genes is a likely mechanism contributing to this risk. The glucocorticoid receptor (GR) gene is of particular interest because of the regulatory role of the GR in hypothalamic–pituitary–adrena...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Tyrka, A R, Parade, S H, Welch, E S, Ridout, K K, Price, L H, Marsit, C, Philip, N S, Carpenter, L L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969762/
https://ncbi.nlm.nih.gov/pubmed/27378548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.112
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