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Essential role of the nuclear isoform of RBFOX1, a candidate gene for autism spectrum disorders, in the brain development

Gene abnormalities in RBFOX1, encoding an mRNA-splicing factor, have been shown to cause autism spectrum disorder and other neurodevelopmental disorders. Since pathophysiological significance of the dominant nuclear isoform in neurons, RBFOX1-isoform1 (iso1), remains to be elucidated, we performed c...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Hamada, Nanako, Ito, Hidenori, Nishijo, Takuma, Iwamoto, Ikuko, Morishita, Rika, Tabata, Hidenori, Momiyama, Toshihiko, Nagata, Koh-Ichi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969621/
https://ncbi.nlm.nih.gov/pubmed/27481563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30805
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