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Prolactin Pro-Differentiation Pathway in Triple Negative Breast Cancer: Impact on Prognosis and Potential Therapy

Triple negative breast cancer (TNBC) is a heterogeneous disease associated with poor clinical outcome and lack of targeted therapy. Here we show that prolactin (PRL) and its signaling pathway serve as a sub-classifier and predictor of pro-differentiation therapy in TNBC. Using immunohistochemistry a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: López-Ozuna, Vanessa M., Hachim, Ibrahim Y., Hachim, Mahmood Y., Lebrun, Jean-Jacques, Ali, Suhad
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969612/
https://ncbi.nlm.nih.gov/pubmed/27480353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30934
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