Disruption of dmc1 Produces Abnormal Sperm in Medaka (Oryzias latipes)

DMC1 is a recombinase that is essential for meiotic synapsis. Experiments in extensive species of eukaryotes have indicated the independent role of DMC1 in repairing double strand breaks (DSBs) produced during meiosis I. Mutation of dmc1 in mice and human often leads to obstacles in spermatogenesis...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chen, Ji, Cui, Xiaojuan, Jia, Shaoting, Luo, Daji, Cao, Mengxi, Zhang, Yunsheng, Hu, Hongling, Huang, Kaiyao, Zhu, Zuoyan, Hu, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969596/
https://ncbi.nlm.nih.gov/pubmed/27480068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30912
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