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Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN

Progressive loss of cardiac myocytes through apoptosis contributes to heart failure (HF). In this study, we tested whether tanshinone IIA, one of the most abundant constituents of the root of Salvia miltiorrhiza, protects rat myocardium-derived H9C2 cells against apoptosis. Treatment of H9C2 cells w...

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Pubblicato in:Am J Transl Res
Autori principali: Zhang, Zhen, Li, Yumei, Sheng, Chuqiao, Yang, Chunfeng, Chen, Liping, Sun, Jinghui
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969449/
https://ncbi.nlm.nih.gov/pubmed/27508033
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