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Inhibition of spinal UCHL1 attenuates pain facilitation in a cancer-induced bone pain model by inhibiting ubiquitin and glial activation

The present study examined alterations of spinal ubiquitin C-terminal hydrolase L1 (UCHL1), ubiquitin expression and glial activation in the cancer-induced bone pain rats. Furthermore, whether inhibition of spinal UCHL1 could alleviate cancer-induced bone pain was observed. The CIBP model was establ...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Cheng, Wei, Chen, Yuan-Li, Wu, Liang, Miao, Bei, Yin, Qin, Wang, Jin-Feng, Fu, Zhi-Jian
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969440/
https://ncbi.nlm.nih.gov/pubmed/27508024
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