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Telomere Length and Health Outcomes: A Two-Sample Genetic Instrumental Variables Analysis

OBJECTIVE: Previous studies linking telomere length (TL) and health have been largely associational. We apply genetic instrumental variables (IV) analysis, also known as Mendelian randomization, to test the hypothesis that shorter TL leads to poorer health. This method reduces bias from reverse caus...

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Detalhes bibliográficos
Publicado no:Exp Gerontol
Main Authors: Hamad, Rita, Walter, Stefan, Rehkopf, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4969151/
https://ncbi.nlm.nih.gov/pubmed/27321645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2016.06.005
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