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Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL
Bromodomain and extraterminal protein (BET) inhibitors suppress the expression of c-MYC. U266, a human myeloma cell line, expresses the MYCL gene, but not the c-MYC gene. Our aim was to analyse the antimyeloma activity of BET inhibitors on U266 cells. Two BET inhibitors, I-BET151 and JQ1, were teste...
Sparad:
| I publikationen: | Anticancer Drugs |
|---|---|
| Huvudupphovsmän: | , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Lippincott Williams & Wilkins
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4969056/ https://ncbi.nlm.nih.gov/pubmed/27276402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0000000000000389 |
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