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Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation
Low extracellular pH promotes in melanoma cells a malignant phenotype characterized by an epithelial-to-mesenchymal transition (EMT) program, endowed with mesenchymal markers, high invasiveness and pro-metastatic property. Here, we demonstrate that melanoma cells exposed to an acidic extracellular m...
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| Publicado no: | Cell Cycle |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968910/ https://ncbi.nlm.nih.gov/pubmed/27266957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1191706 |
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