Potential predictive role of chemotherapy-induced changes of soluble CD40 ligand in untreated advanced pancreatic ductal adenocarcinoma

Pancreas ductal adenocarcinoma lacks predictive biomarkers. CD40 is a member of the tumor necrosis factor superfamily. CD40–sCD40L interaction is considered to contribute to the promotion of tumor cell growth and angiogenesis. The aim of the present study was to investigate the role of serum sCD40L...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Azzariti, Amalia, Brunetti, Oronzo, Porcelli, Letizia, Graziano, Giusi, Iacobazzi, Rosa Maria, Signorile, Michele, Scarpa, Aldo, Lorusso, Vito, Silvestris, Nicola
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968860/
https://ncbi.nlm.nih.gov/pubmed/27555786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S106496
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