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Epigenetic induction of adaptive immune response in multiple myeloma: sequential azacitidine and lenalidomide generate cancer testis antigen-specific cellular immunity

Patients with multiple myeloma (MM) undergoing high dose therapy and autologous stem cell transplantation (SCT) remain at risk for disease progression. Induction of the expression of highly immunogenic cancer testis antigens (CTA) in malignant plasma cells in MM patients may trigger a protective imm...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Toor, Amir A., Payne, Kyle K., Chung, Harold M., Sabo, Roy T., Hazlett, Allison F., Kmieciak, Maciej, Sanford, Kimberly, Williams, David C., Clark, William B., Roberts, Catherine H., McCarty, John M., Manjili, Masoud H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968567/
https://ncbi.nlm.nih.gov/pubmed/22816680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2012.09225.x
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