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Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations

BACKGROUND: The Mouse Genomes Project is an ongoing collaborative effort to sequence the genomes of the common laboratory mouse strains. In 2011, the initial analysis of sequence variation across 17 strains found 56.7 M unique single nucleotide polymorphisms (SNPs) and 8.8 M indels. We carry out dee...

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Publicat a:Genome Biol
Autors principals: Doran, Anthony G., Wong, Kim, Flint, Jonathan, Adams, David J., Hunter, Kent W., Keane, Thomas M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968449/
https://ncbi.nlm.nih.gov/pubmed/27480531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1024-y
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