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Snapshot Hyperspectral Light-Sheet Imaging of Signal Transduction in Live Pancreatic Islets

The observation of ionic signaling dynamics in intact pancreatic islets has contributed greatly to our understanding of both α- and β-cell function. Insulin secretion from β-cells depends on the firing of action potentials and consequent rises of intracellular calcium activity ([Ca(2+)](i)). Zinc (Z...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Lavagnino, Zeno, Dwight, Jason, Ustione, Alessandro, Nguyen, Thuc-Uyen, Tkaczyk, Tomasz S., Piston, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968423/
https://ncbi.nlm.nih.gov/pubmed/27463142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.06.014
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