Mechanistic study of TRPM2-Ca(2+)-CAMK2-BECN1 signaling in oxidative stress-induced autophagy inhibition

Reactive oxygen species (ROS) have been commonly accepted as inducers of autophagy, and autophagy in turn is activated to relieve oxidative stress. Yet, whether and how oxidative stress, generated in various human pathologies, regulates autophagy remains unknown. Here, we mechanistically studied the...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Wang, Qian, Guo, Wenjing, Hao, Baixia, Shi, Xianli, Lu, Yingying, Wong, Connie W.M., Ma, Victor W.S., Yip, Timothy T.C., Au, Joseph S.K., Hao, Quan, Cheung, King-Ho, Wu, Wutian, Li, Gui-Rong, Yue, Jianbo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968236/
https://ncbi.nlm.nih.gov/pubmed/27245989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2016.1187365
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