PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression

Although autophagy is most critical for survival of cancer cells, especially in fast-growing tumors, the mechanism remains to be fully characterized. Herein we report that PSMD10/gankyrin promotes autophagy in hepatocellular carcinoma (HCC) in response to starvation or stress through 2 complementary...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Luo, Tao, Fu, Jing, Xu, An, Su, Bo, Ren, Yibing, Li, Ning, Zhu, Junjie, Zhao, Xiaofang, Dai, Rongyang, Cao, Jie, Wang, Bibo, Qin, Wenhao, Jiang, Jinhua, Li, Juan, Wu, Mengchao, Feng, Gensheng, Chen, Yao, Wang, Hongyang
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Basic Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968225/
https://ncbi.nlm.nih.gov/pubmed/25905985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1034405
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