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Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress

During autophagy, double-membrane autophagosomes are observed in the cytoplasm. Thus, extensive studies have focused on autophagic turnover of cytoplasmic material. Whether autophagy has a role in degrading nuclear constituents is poorly understood. We reveal that the autophagy protein LC3/Atg8 dire...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Dou, Zhixun, Ivanov, Andrejs, Adams, Peter D., Berger, Shelley L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968220/
https://ncbi.nlm.nih.gov/pubmed/26654219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1127465
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