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Clinical Significance of Symptoms in Smokers with Preserved Pulmonary Function

BACKGROUND: Currently, the diagnosis of chronic obstructive pulmonary disease (COPD) requires a ratio of forced expiratory volume in 1 second (FEV(1)) to forced vital capacity (FVC) of less than 0.70 as assessed by spirometry after bronchodilator use. However, many smokers who do not meet this defin...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Woodruff, Prescott G., Barr, R. Graham, Bleecker, Eugene, Christenson, Stephanie A., Couper, David, Curtis, Jeffrey L., Gouskova, Natalia A., Hansel, Nadia N., Hoffman, Eric A., Kanner, Richard E., Kleerup, Eric, Lazarus, Stephen C., Martinez, Fernando J., Paine, Robert, Rennard, Stephen, Tashkin, Donald P., Han, MeiLan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968204/
https://ncbi.nlm.nih.gov/pubmed/27168432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1505971
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