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Neuroprotective effect of preoperatively induced mild hypothermia as determined by biomarkers and histopathological estimation in a rat subdural hematoma decompression model

OBJECT: In traumatic brain injury (TBI) patients, hypothermia therapy has not shown efficacy in multicenter clinical trials. With the post-hoc data from the latest clinical trial (NABIS:H II), we hypothesized that hypothermia may be beneficial in the rat acute subdural hematoma (ASDH) model by blunt...

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Detalhes bibliográficos
Publicado no:J Neurosurg
Main Authors: Yokobori, Shoji, Gajavelli, Shyam, Mondello, Stefania, Mo-Seaney, Jixiang, Hayes, Ronald L, Bramlett, Helen M., Dietrich, W. Dalton, Bullock, M. Ross
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968198/
https://ncbi.nlm.nih.gov/pubmed/23140154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2012.10.JNS12725
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