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c-Jun N-terminal kinase-mediated Rubicon expression enhances hepatocyte lipoapoptosis and promotes hepatocyte ballooning

AIM: To clarify the relationship between autophagy and lipotoxicity-induced apoptosis, which is termed “lipoapoptosis,” in non-alcoholic steatohepatitis. METHODS: Male C57BL/6J mice were fed a high-fat diet (HFD) for 12 wk, after which the liver histology and expression of proteins such as p62 or LC...

詳細記述

保存先:
書誌詳細
出版年:World J Gastroenterol
主要な著者: Suzuki, Akiko, Kakisaka, Keisuke, Suzuki, Yuji, Wang, Ting, Takikawa, Yasuhiro
フォーマット: Artigo
言語:Inglês
出版事項: Baishideng Publishing Group Inc 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968130/
https://ncbi.nlm.nih.gov/pubmed/27605885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i28.6509
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