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Quantitation and pharmacokinetic modeling of therapeutic antibody quality attributes in human studies
A thorough understanding of drug metabolism and disposition can aid in the assessment of efficacy and safety. However, analytical methods used in pharmacokinetics (PK) studies of protein therapeutics are usually based on ELISA, and therefore can provide a limited perspective on the quality of the dr...
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Gepubliceerd in: | MAbs |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Taylor & Francis
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968108/ https://ncbi.nlm.nih.gov/pubmed/27216574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1186322 |
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