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Role of p34cdc2-mediated phosphorylations in two-step activation of pp60c-src during mitosis.

Phosphorylation of pp60c-src by p34cdc2 at three amino-proximal serine/threonine residues is temporally correlated with, but insufficient for, mitotic activation of c-Src kinase. The direct cause of activation during mitosis appears to be temporally correlated partial dephosphorylation of Tyr-527, a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Shenoy, S, Chackalaparampil, I, Bagrodia, S, Lin, P H, Shalloway, D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49681/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1379736/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.7237
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