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Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases
Mapping the molecular circuits that are perturbed by genetic variants underlying complex traits and diseases remains a great challenge. We present a comprehensive resource of 394 cell type and tissue-specific gene regulatory networks for human, each specifying the genome-wide connectivity between tr...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967716/ https://ncbi.nlm.nih.gov/pubmed/26950747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3799 |
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