RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications

Despite therapeutic improvements, a sizable number of patients with T-cell acute lymphoblastic leukemia still have a poor outcome. To unravel the genomic background associated with refractoriness, we evaluated the transcriptome of 19 cases of refractory/early relapsed T-cell acute lymphoblastic leuk...

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Veröffentlicht in:Haematologica
Hauptverfasser: Gianfelici, Valentina, Chiaretti, Sabina, Demeyer, Sofie, Di Giacomo, Filomena, Messina, Monica, La Starza, Roberta, Peragine, Nadia, Paoloni, Francesca, Geerdens, Ellen, Pierini, Valentina, Elia, Loredana, Mancini, Marco, De Propris, Maria Stefania, Apicella, Valerio, Gaidano, Gianluca, Testi, Anna Maria, Vitale, Antonella, Vignetti, Marco, Mecucci, Cristina, Guarini, Anna, Cools, Jan, Foà, Robin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967573/
https://ncbi.nlm.nih.gov/pubmed/27151993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.139410
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