Dermorphin-related peptides from the skin of Phyllomedusa bicolor and their amidated analogs activate two mu opioid receptor subtypes that modulate antinociception and catalepsy in the rat.

Three naturally occurring dermorphin-like peptides from the skin of the frog Phyllomedusa bicolor, the related carboxyl-terminal amides, and some substituted analogs were synthesized, their binding profiles to opioid receptors were determined, and their biological activities were studied in isolated...

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Bibliografski detalji
Glavni autori: Negri, L, Erspamer, G F, Severini, C, Potenza, R L, Melchiorri, P, Erspamer, V
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC49674/
https://ncbi.nlm.nih.gov/pubmed/1353890
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