The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism

AIMS/HYPOTHESIS: Potentiation of glucose-induced insulin secretion is the main mechanism of exenatide (EXE) antidiabetic action, however, increased glucose utilization by peripheral tissues has been also reported. We here studied the effect of EXE on glucose uptake by skeletal muscle cells. METHODS:...

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Vydáno v:J Transl Med
Hlavní autoři: Andreozzi, Francesco, Raciti, Gregory Alexander, Nigro, Cecilia, Mannino, Gaia Chiara, Procopio, Teresa, Davalli, Alberto M., Beguinot, Francesco, Sesti, Giorgio, Miele, Claudia, Folli, Franco
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967343/
https://ncbi.nlm.nih.gov/pubmed/27473212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0985-7
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