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A network based approach to drug repositioning identifies plausible candidates for breast cancer and prostate cancer

BACKGROUND: The high cost and the long time required to bring drugs into commerce is driving efforts to repurpose FDA approved drugs—to find new uses for which they weren’t intended, and to thereby reduce the overall cost of commercialization, and shorten the lag between drug discovery and availabil...

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Pubblicato in:BMC Med Genomics
Autori principali: Chen, Hsiao-Rong, Sherr, David H., Hu, Zhenjun, DeLisi, Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967295/
https://ncbi.nlm.nih.gov/pubmed/27475327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-016-0212-7
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