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Heterotrimeric G protein signaling in polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is a signalopathy of renal tubular epithelial cells caused by naturally occurring mutations in two distinct genes, polycystic kidney disease 1 (PKD1) and 2 (PKD2). Genetic variants in PKD1, which encodes the polycystin-1 (PC-1) protein, remain the...
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| Veröffentlicht in: | Physiol Genomics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4967223/ https://ncbi.nlm.nih.gov/pubmed/27199453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00027.2016 |
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