Activation of calpain by renin-angiotensin system in pleural mesothelial cells mediates tuberculous pleural fibrosis

Pleural fibrosis is defined as an excessive deposition of extracellular matrix (ECM) components that results in destruction of the normal pleural tissue architecture. It can result from diverse inflammatory conditions, especially tuberculous pleurisy. Pleural mesothelial cells (PMCs) play a pivotal...

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Udgivet i:Am J Physiol Lung Cell Mol Physiol
Main Authors: Yang, Jie, Xiang, Fei, Cai, Peng-Cheng, Lu, Yu-Zhi, Xu, Xiao-Xiao, Yu, Fan, Li, Feng-Zhi, Greer, Peter A., Shi, Huan-Zhong, Zhou, Qiong, Xin, Jian-Bao, Ye, Hong, Su, Yunchao, Ma, Wan-Li
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
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Call for Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967195/
https://ncbi.nlm.nih.gov/pubmed/27261452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00348.2015
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