Skeletal Muscle Mitochondrial Content, Oxidative Capacity, and Mfn2 Expression are Reduced in Older Patients with Heart Failure and Preserved Ejection Fraction and are Related to Exercise Intolerance

OBJECTIVES: The aim of this study was to examine skeletal muscle mitochondria content, oxidative capacity, and the expression of key mitochondrial dynamics proteins in patients with heart failure with preserved ejection fraction (HFpEF) and to determine potential relationships with measures of exerc...

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Detalhes bibliográficos
Publicado no:JACC Heart Fail
Main Authors: Molina, Anthony J. A., Bharadwaj, Manish S., Van Horn, Cynthia, Nicklas, Barbara J., Lyles, Mary F., Eggebeen, Joel, Haykowsky, Mark J., Brubaker, Peter H., Kitzman, Dalane W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967040/
https://ncbi.nlm.nih.gov/pubmed/27179829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchf.2016.03.011
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