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Association of concurrent acid-suppression therapy with survival outcomes and adverse event incidence in oncology patients receiving erlotinib

PURPOSE: Acid-suppression therapy is known to decrease the systemic exposure of erlotinib. The erlotinib prescribing information also recommends staggering dosing with a histamine-2 receptor antagonist (H(2)RA) and avoiding concurrent use of a proton-pump inhibitor (PPI). This retrospective analysis...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Lam, Lisa H., Capparelli, Edmund V., Kurzrock, Razelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967016/
https://ncbi.nlm.nih.gov/pubmed/27372908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3087-6
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