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Adjacent Codons Act in Concert to Modulate Translation Efficiency in Yeast

Translation elongation efficiency is largely thought of as the sum of decoding efficiencies for individual codons. Here, we find that adjacent codon pairs modulate translation efficiency. Deploying an approach in Saccharomyces cerevisiae that scored the expression of over 35,000 GFP variants in whic...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Gamble, Caitlin E., Brule, Christina E., Dean, Kimberly M., Fields, Stanley, Grayhack, Elizabeth J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967012/
https://ncbi.nlm.nih.gov/pubmed/27374328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.070
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