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Tetrahymena Poc1 ensures proper intertriplet microtubule linkages to maintain basal body integrity

Basal bodies comprise nine symmetric triplet microtubules that anchor forces produced by the asymmetric beat pattern of motile cilia. The ciliopathy protein Poc1 stabilizes basal bodies through an unknown mechanism. In poc1∆ cells, electron tomography reveals subtle defects in the organization of in...

詳細記述

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書誌詳細
出版年:Mol Biol Cell
主要な著者: Meehl, Janet B., Bayless, Brian A., Giddings, Thomas H., Pearson, Chad G., Winey, Mark
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966981/
https://ncbi.nlm.nih.gov/pubmed/27251062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0165
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