An Improved System for Generation of Diploid Cloned Porcine Embryos Using Induced Pluripotent Stem Cells Synchronized to Metaphase

Pigs provide outstanding models of human genetic diseases due to their striking similarities with human anatomy, physiology and genetics. Although transgenic pigs have been produced using genetically modified somatic cells and nuclear transfer (SCNT), the cloning efficiency was extremely low. Here,...

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Udgivet i:PLoS One
Main Authors: Kim, Eunhye, Zheng, Zhong, Jeon, Yubyeol, Jin, Yong-Xun, Hwang, Seon-Ung, Cai, Lian, Lee, Chang-Kyu, Kim, Nam-Hyung, Hyun, Sang-Hwan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966966/
https://ncbi.nlm.nih.gov/pubmed/27472781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160289
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