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PhyloBot: A Web Portal for Automated Phylogenetics, Ancestral Sequence Reconstruction, and Exploration of Mutational Trajectories

The method of phylogenetic ancestral sequence reconstruction is a powerful approach for studying evolutionary relationships among protein sequence, structure, and function. In particular, this approach allows investigators to (1) reconstruct and “resurrect” (that is, synthesize in vivo or in vitro)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Hanson-Smith, Victor, Johnson, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966924/
https://ncbi.nlm.nih.gov/pubmed/27472806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004976
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