The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

Systemic infection with Streptococcus pneumoniae is associated with a vigorous pro-inflammatory response to structurally complex cell wall fragments (PnCW) that are shed during cell growth and antibiotic-induced autolysis. Consistent with previous studies, inflammatory cytokine production induced by...

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Publicado no:Cell Microbiol
Main Authors: Moreira, Lilian O., El Kasmi, Karim C., Smith, Amber M., Finkelstein, David, Fillon, Sophie, Kim, Yun-Gi, Núñez, Gabriel, Tuomanen, Elaine, Murray, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966886/
https://ncbi.nlm.nih.gov/pubmed/18549453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2008.01189.x
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