Immunotherapeutic targeting of LIGHT/LTβR/HVEM pathway fully recapitulates the reduced cytotoxic phenotype of LIGHT-deficient T cells

Tumor necrosis factor (TNF)/TNF receptor (TNFR) superfamily members play essential roles in the development of the different phases of the immune response. Mouse LIGHT (TNFSF14) is a type II transmembrane protein with a C-terminus extracellular TNF homology domain (THD) that assembles in homotrimers...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:MAbs
Asıl Yazarlar: del Rio, Maria-Luisa, Fernandez-Renedo, Carlos, Chaloin, Olivier, Scheu, Stefanie, Pfeffer, Klaus, Shintani, Yasushi, Perez-Simon, Jose-Antonio, Schneider, Pascal, Rodriguez-Barbosa, Jose-Ignacio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2016
Konular:
Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966841/
https://ncbi.nlm.nih.gov/pubmed/26752542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1132130
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