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Telomere length shortening is associated with treatment-free remission in chronic myeloid leukemia patients

We studied telomere length in 32 CML patients who discontinued imatinib after achieving complete molecular remission and 32 age-sex-matched controls. The relative telomere length (RTL) was determined by q-PCR as the telomere to single copy gene (36B4) ratio normalized to a reference sample (K-562 DN...

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Publicat a:J Hematol Oncol
Autors principals: Caocci, Giovanni, Greco, Marianna, Delogu, Giuseppe, Secchi, Christian, Martino, Bruno, Labate, Claudia, Abruzzese, Elisabetta, Trawinska, Malgorzata Monika, Galimberti, Sara, Orru, Federica, Fozza, Claudio, Passerini, Carlo Gambacorti, Galimi, Francesco, La Nasa, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966800/
https://ncbi.nlm.nih.gov/pubmed/27473052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0293-y
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